Suppression of malignancy in hybrid cells: the mechanism
نویسندگان
چکیده
منابع مشابه
Suppression of malignancy in hybrid cells: the mechanism.
When malignant cells, defined by their ability to grow progressively in genetically compatible hosts, are fused with diploid fibroblasts of the same species, the resulting hybrid cells, so long as they retain certain specific chromosomes donated by the diploid parent cell, are non-malignant. When these particular chromosomes are eliminated from the hybrid, the malignant phenotype reappears, and...
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ژورنال
عنوان ژورنال: Journal of Cell Science
سال: 1985
ISSN: 1477-9137,0021-9533
DOI: 10.1242/jcs.79.1.83